Preoperative Microvascular Dysfunction: A Prospective, Observational Study Expanding Risk Assessment Strategies in Major Thoracic Surgery
Robert Schier, Jochen Hinkelbein, Hanke Marcus, Reza Mehran, Randa El-Zein, Wayne Hofstetter, Joseph Swafford, Bernhard Riedel
ANNALS OF THORACIC SURGERY | ELSEVIER SCIENCE INC | Published : 2012
BACKGROUND: Brachial artery reactivity testing (BART)--a surrogate test of microvascular function--predicts cardiac risk in the nonsurgical population and associates it with adverse outcome after vascular surgery. This pilot study investigated BART-derived variables, including flow-mediated dilation (FMD), in preoperative risk stratification for major thoracic surgery. METHODS: After institutional review board approval, BART was performed in 63 patients before major thoracic surgery. Ultrasonography recorded two-dimensional images and Doppler flow signals of the brachial artery preoperatively at baseline and after induced reactive hyperemia. Variables derived using BART were correlated with ..View full abstract
This study was supported by IARS grant funding.