Journal article
Effect of pneumococcal vaccination on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian children
EM Dunne, J Manning, FM Russell, RM Robins-Browne, EK Mulholland, C Satzke
Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 2012
DOI: 10.1128/JCM.06589-11
Abstract
The 7-valent pneumococcal conjugate vaccine (PCV7) reduces carriage of vaccine type Streptococcus pneumoniae but leads to replacement by nonvaccine serotypes and may affect carriage of other respiratory pathogens. We investigated nasopharyngeal carriage of S. pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian infants participating in a pneumococcal vaccine trial using quantitative PCR. Vaccination did not affect pathogen carriage rates or densities, whereas significant differences between the two major ethnic groups were observed. Copyright © 2012, American Society for Microbiology. All Rights Reserved.
Grants
Funding Acknowledgements
This work was supported by funding from the Murdoch Childrens Research Institute and the Victorian Government's Operational Infrastructure Support Program.