Journal article

Weight change and prostate cancer incidence and mortality

Julie K Bassett, Gianluca Severi, Laura Baglietto, Robert J MacInnis, Hoa N Hoang, John L Hopper, Dallas R English, Graham G Giles

INTERNATIONAL JOURNAL OF CANCER | WILEY | Published : 2012

Abstract

The relationship between obesity and prostate cancer risk has been studied extensively but with inconsistent findings, particularly for tumor aggressiveness. Few studies have investigated weight change and prostate cancer incidence or mortality. Using the Melbourne Collaborative Cohort Study, which recruited 17,045 men aged between 40 and 69 years at study entry, we investigated associations between reported weight and body mass index (BMI) at age 18 and measured at study entry, height, weight change between age 18 and study entry and prostate cancer incidence and mortality. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression. During follow-up (mean = 1..

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