Journal article

Effect of Long-Term Vigorous Physical Activity on Healthy Adult Knee Cartilage

Andrew J Teichtahl, Anita Wluka, Yuanyuan Wang, Andrew Forbes, Miranda L Davies-Tuck, Dallas R English, Graham G Giles, Flavia M Cicuttini



INTRODUCTION: Whether participation in long-term vigorous physical activity affects knee cartilage is unclear and may depend on the state of knee health. We examined the association between vigorous physical activity during a decade and the subsequent changes in knee cartilage among healthy adults. We then examined whether this effect differed in those with and without bone marrow lesions (BMLs), as an indicator of preclinical joint damage. METHODS: A total of 297 healthy adults age 50-79 yr were recruited. Physical activity was assessed via questionnaire at baseline (1990-1994) and at follow-up (2003-2004), and a score for persistence of vigorous physical activity score was determined. Each..

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Awarded by National Health and Medical Research Council (NHMRC)

Awarded by NHMRC Public Health (Australia)

Funding Acknowledgements

This study was funded by a program grant from the National Health and Medical Research Council (NHMRC 209057) and was further supported by infrastructure provided by The Cancer Council of Victoria.r The authors thank the study participants who made this study possible. The Melbourne Collaborative Cohort Study recruitment was funded by VicHealth and The Cancer Council of Victoria.r The authors thank the NHMRC (project grant 334150) for support. Dr. Wluka is a recipient of an NHMRC Career Development Award (clinical level 1, 545876). Dr. Wang is a recipient of an NHMRC Public Health (Australia) Fellowship (NHMRC 465142). Dr. Davies-Tuck is a recipient of an Australian Postgraduate Award. No author has a professional relationship with companies or manufacturers who will benefit from the results of the present study.