Autonomic dysfunction in children with sleep disordered breathing
Lisa M Walter, Gillian M Nixon, Margot J Davey, Vicki Anderson, Adrian M Walker, Rosemary SC Horne
SLEEP AND BREATHING | SPRINGER HEIDELBERG | Published : 2013
PURPOSE: Sleep disordered breathing (SDB) has adverse effects on cardiovascular health in adults, partly due to changes in autonomic activity. However, there have been limited studies in children. We analysed the impact of SDB and sleep stage on autonomic control of heart rate in 7-12-year-old children, utilizing spectral heart rate variability (HRV) as a measure of autonomic activity. METHODS: Eighty children underwent overnight polysomnography. Subjects were grouped according to their obstructive apnoea-hypopnoea index (OAHI): controls, OAHI ≤1 event/h and no history of snoring; primary snorers (PS) OAHI ≤1, Mild (OAHI 1-5) and moderate/severe (MS) OAHI >5. HRV was analysed during Wake, no..View full abstract
Awarded by National Health and Medical Research Council of Australia
Funding for this project was awarded by the National Health and Medical Research Council of Australia [Project Grant Number 384142] and supported by the Victorian Government's Operational Infrastructure Support Program.