Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity
Susanne C Feil, Sara Lawrence, Terrence D Mulhern, Jessica K Holien, Eileen M Hotze, Stephen Farrand, Rodney K Tweten, Michael W Parker
Structure | CELL PRESS | Published : 2012
Awarded by National Institutes of Health
This research was partly undertaken on the MX1 and SAXS/WAXS beamlines at the Australian Synchrotron, Victoria, Australia. We thank Dr. Julian Adams and the other beamline staff for their assistance. We also thank David Ascher for help with mass spectrometry and Dr. Paul Rams land for expert comments on our manuscript. We thank Dr. Mike Kuiper for his help in the preparation of the graphical abstract. This work was partly carried out in the Australian Cancer Research Foundation Rational Drug Discovery Facility. This work was also supported by a grant from the National Health and Medical Research Council of Australia (NHMRC) to M.W.P. and funding from the Victorian Government Operational Infrastructure Support Scheme to St Vincent's Institute. R.K.T. received support from Grant AI037657 from the National Institutes of Health. S.C.F. was supported by a NHMRC Industry Fellowship. M.W.P. is an Australian Research Council Federation Fellow and NHMRC Honorary Fellow.