Journal article
Fluid recovery during lung lavage in meconium aspiration syndrome
PA Dargaville, B Copnell, JF Mills, I Haron, JKF Lee, DG Tingay, J Rohana, LF Mildenhall, MJY Jeng, A Narayanan, MR Battin, CA Kuschel, JL Sadowsky, H Patel, CJ Kilburn, JB Carlin, CJ Morley
Acta Paediatrica International Journal of Paediatrics | WILEY-BLACKWELL | Published : 2013
DOI: 10.1111/apa.12070
Abstract
Lung lavage using two aliquots of 15 mL/kg of dilute surfactant was performed in 30 ventilated infants with severe meconium aspiration syndrome (MAS). Mean recovery of instilled lavage fluid was 46%, with greater fluid return associated with lower mean airway pressure at 24 h and a shorter duration of respiratory support. Conclusion Recovery of instilled lavage fluid is paramount in effective lung lavage in MAS and must be afforded priority in the lavage technique. © 2012 Foundation Acta Pædiatrica.
Grants
Awarded by Australian National Health and Medical Research Council
Funding Acknowledgements
We thank Francesca Orsini for assisting with the statistical analysis. Supported by grants from the Australian National Health and Medical Research Council (Nos. 284539 and 384100) and the Murdoch Children Research Institute. Abbott Pty. Ltd. provided surfactant for lung lavage. The funding sources had no role in the study design, data collection, data analysis or preparation of the report.