Journal article

Vβ profile in toxic shock syndrome: A possible diagnostic test

CM MacIsaac, N Curtis, J Cade, K Visvanathan

International Congress Series | Published : 2006

Abstract

There is currently no diagnostic test for Toxic shock syndrome (TSS) which is caused by superantigens (SAg). SAg bind to the lateral aspect of a T cell receptor at its Vβ region. We studied the expression of Vβ segments on circulating T cells from 7 patients with TSS and 11 controls. The Vβ profile was abnormal in all patients. This could in the future be a possible diagnostic test for TSS. © 2005 Elsevier B.V. All rights reserved.