Journal article
Factors associated with thrombotic complications after the fontan procedure: A secondary analysis of a multicenter, randomized trial of primary thromboprophylaxis for 2 years after the fontan procedure
BW McCrindle, C Manlhiot, A Cochrane, R Roberts, M Hughes, B Szechtman, R Weintraub, M Andrew, P Monagle
Journal of the American College of Cardiology | Published : 2013
Abstract
Objectives: The study sought to identify factors associated with increased risk of thrombosis after Fontan. Background: The Fontan procedure is the culmination of staged palliation for patients with univentricular physiology. Thrombosis is an important complication after this procedure. Methods: An international multicenter randomized controlled trial of acetylsalicylic acid versus warfarin for thromboprophylaxis after the Fontan procedure was conducted in 111 patients, and did not show a significant difference regarding thrombotic complications. We performed a secondary analysis of this previously published manuscript to identify factors associated with thrombosis in this population. Standa..
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Awarded by Heart and Stroke Foundation of Canada
Funding Acknowledgements
This work was supported by a research grant from the Heart and Stroke Foundation of Ontario (grant-in-aid NA-3565), National Heart Foundation of Australia project grant, the Henderson Research Centre, Hamilton, and the CIBC World Markets Children's Miracle Foundation. Mr. Roberts is a statistical consultant for Coaxia Inc. and Bayer Healthcare. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. A version of this paper was presented at the 2008 Scientific Sessions of the American Heart Association, November 8 to 12, 2008, New Orleans, Louisiana. Dr. Andrew is now deceased.