Functional magnetic resonance imaging: Focus localization

Abstract

Precise seizure focus localization and unraveling different structures involved in the genesis of the epileptic process is a major challenge that faces epilepsy research. The combination of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is a well-established method that offers the unique advantage of measuring noninvasively specific hemodynamic changes related to epileptic discharges, providing unique localizing information on seizure foci and different cortical and subcortical structures that may be involved in this process. In addition, functional connectivity studies are emerging as a promising tool that can be used to interrogate epileptic networks and poss..