Physical fitness and reverse cholesterol transport.
Beata Olchawa, Bronwyn A Kingwell, Anh Hoang, Laurence Schneider, Osamu Miyazaki, Paul Nestel, Dmitri Sviridov
Arterioscler Thromb Vasc Biol | Published : 2004
BACKGROUND: Physical exercise is associated with a decreased risk of cardiovascular disease, which may be partly caused by the effect of exercise on the lipoprotein profile. The most consistent effect of exercise on lipoprotein metabolism is an increase in high-density lipoprotein (HDL). METHODS AND RESULTS: Parameters of reverse cholesterol transport (RCT) in 25 endurance-trained male athletes were compared with 33 age-matched males enjoying an active lifestyle. VO2max was higher in athletes than in controls (53.4+/-1.2 versus 38.8+/-1.0 mL/min per kg; P<0.01). The following differences in parameters of RCT were found: (1) plasma HDL cholesterol and apoA-I levels were higher in athletes com..View full abstract