Journal article

p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: Possible implications for melanoma progression

EV Sviderskaya, VC Gray-Schopfer, SP Hill, NP Smit, TJ Evans-Whipp, J Bond, L Hill, V Bataille, G Peters, D Kipling, D Wynford-Thomas, DC Bennett

JOURNAL OF THE NATIONAL CANCER INSTITUTE | OXFORD UNIV PRESS INC | Published : 2003

DOI: 10.1093/jnci/95.10.723

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Keywords

Cellular Senescence
Telomerase
Life-Span
Cyclin-Dependent Kinase Inhibitor P16
Dna-Binding Proteins
Tumor-Suppressor
Induced Pigmentation
Karyotyping
Science & Technology
Cyclin-Dependent Kinase Inhibitor P21
Humans
Cell Line, Transformed
Kinetics
Phenotype
Disease Progression
Apoptosis
Cyclins
Melanocytes
Life Sciences & Biomedicine
Familial Melanoma
Ink4a Locus
Malignant-Melanoma
Immunoblotting
Human-Diploid Fibroblasts
Gene Expression Regulation, Neoplastic
P16(ink4a)
Melanoma
Human-Cells
Oncology