Journal article

p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: Possible implications for melanoma progression

EV Sviderskaya, VC Gray-Schopfer, SP Hill, NP Smit, TJ Evans-Whipp, J Bond, L Hill, V Bataille, G Peters, D Kipling, D Wynford-Thomas, DC Bennett

JOURNAL OF THE NATIONAL CANCER INSTITUTE | OXFORD UNIV PRESS INC | Published : 2003

DOI: 10.1093/jnci/95.10.723

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Keywords

Tumor-Suppressor
P16(ink4a)
Telomerase
Humans
Cell Line, Transformed
Melanoma
Oncology
Familial Melanoma
Melanocytes
Life Sciences & Biomedicine
Human-Cells
Ink4a Locus
Malignant-Melanoma
Cyclins
Phenotype
Dna-Binding Proteins
Apoptosis
Cyclin-Dependent Kinase Inhibitor P16
Life-Span
Disease Progression
Immunoblotting
Cellular Senescence
Gene Expression Regulation, Neoplastic
Kinetics
Science & Technology
Cyclin-Dependent Kinase Inhibitor P21
Human-Diploid Fibroblasts
Karyotyping
Induced Pigmentation