Journal article

Clopidogrel hyper-response and bleeding risk in neurointerventional procedures

C Goh, L Churilov, P Mitchell, R Dowling, B Yan

American Journal of Neuroradiology | AMER SOC NEURORADIOLOGY | Published : 2013

Abstract

BACKGROUND AND PURPOSE: Antiplatelet therapy is associated with decreased ischemic events after neurointerventional procedures. Antiplatelet resistance negates the protective effects of antiplatelet medication, leading to a higher incidence of ischemic events. A possible link between antiplatelet hyper-response and increased hemorrhagic complications has been inadequately investigated. We aimed to examine the correlation between antiplatelet hyper-response and the risk of hemorrhagic complications. MATERIALS AND METHODS: Patients who were treated with antiplatelet medications and underwent neurointerventional procedures were prospectively recruited. We collected the following data: demograph..

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