Journal article
Cost-effectiveness of artemisinin combination therapy for uncomplicated malaria in children: data from Papua New Guinea
Wendy A Davis, Philip M Clarke, Peter M Siba, Harin A Karunajeewa, Carol Davy, Ivo Mueller, Timothy ME Davis
BULLETIN OF THE WORLD HEALTH ORGANIZATION | WORLD HEALTH ORGANIZATION | Published : 2011
Abstract
OBJECTIVE: To compare the cost-effectiveness of conventional antimalarial therapy with that of three artemisinin combination treatment regimens in children from Papua New Guinea aged 6 to 60 months. METHODS: An incremental cost-effectiveness analysis was performed using data from 656 children with Plasmodium falciparum and/or P. vivax malaria who participated in a large intervention trial in two clinics in northern Papua New Guinea. The children were randomized to one of the following groups: (i) conventional treatment with chloroquine plus sulfadoxine plus pyrimethamine (CQ+S+P); (ii) artesunate plus S plus P; (iii) dihydroartemisinin plus piperaquine (DHA+PQ); and (iv) artemether plus lume..
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Awarded by National Health and Medical Research Council of Australia
Funding Acknowledgements
Funding: The main trial was sponsored by WHO Western Pacific Region, Rotary Against Malaria (Papua New Guinea) and the National Health and Medical Research Council of Australia (grant 353663). TMED was supported by an NHMRC Practitioner Fellowship.