Journal article

Cost-effectiveness of artemisinin combination therapy for uncomplicated malaria in children: data from Papua New Guinea

Wendy A Davis, Philip M Clarke, Peter M Siba, Harin A Karunajeewa, Carol Davy, Ivo Mueller, Timothy ME Davis

BULLETIN OF THE WORLD HEALTH ORGANIZATION | WORLD HEALTH ORGANIZATION | Published : 2011

Abstract

OBJECTIVE: To compare the cost-effectiveness of conventional antimalarial therapy with that of three artemisinin combination treatment regimens in children from Papua New Guinea aged 6 to 60 months. METHODS: An incremental cost-effectiveness analysis was performed using data from 656 children with Plasmodium falciparum and/or P. vivax malaria who participated in a large intervention trial in two clinics in northern Papua New Guinea. The children were randomized to one of the following groups: (i) conventional treatment with chloroquine plus sulfadoxine plus pyrimethamine (CQ+S+P); (ii) artesunate plus S plus P; (iii) dihydroartemisinin plus piperaquine (DHA+PQ); and (iv) artemether plus lume..

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