Journal article

Defensinpred: defensin and defensin types prediction server.

S Ramya Kumari, Ritesh Badwaik, Vijayaraghavan Sundararajan, VK Jayaraman

Protein Pept Lett | Bentham Science Publishers Ltd. | Published : 2012

Abstract

Defensins are considered to play an important role in the innate immune system of virtually all life forms, from insects and plants to amphibians and mammals. They are classified into alpha, beta and theta-defensins. Fast and accurate computational prediction of defensin and defensin types will help in annotating unidentified defensin novel peptides. Identified defensins, owing to their small length and potent antimicrobial activity can be used effectively for development of new clinically applicable antibiotics. Thus predicting the defensin candidates will aid in accurate identification of novel peptide drugs. Support vector machines prediction model accuracy was 99% for defensin and defens..

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