Journal article
Nasogastric hydration versus intravenous hydration for infants with bronchiolitis: A randomised trial
E Oakley, M Borland, J Neutze, J Acworth, D Krieser, S Dalziel, A Davidson, S Donath, K Jachno, M South, T Theophilos, FE Babl
Lancet Respiratory Medicine | Published : 2013
Abstract
Background: Bronchiolitis is the most common lower respiratory tract infection in infants and the leading cause of hospital admission. Hydration is a mainstay of treatment, but insufficient evidence exists to guide clinical practice. We aimed to assess whether intravenous hydration or nasogastric hydration is better for treatment of infants. Methods: In this multicentre, open, randomised trial, we enrolled infants aged 2-12 months admitted to hospitals in Australia and New Zealand with a clinical diagnosis of bronchiolitis during three bronchiolitis seasons (April 1-Oct 31, in 2009, 2010, and 2011). We randomly allocated infants to nasogastric hydration or intravenous hydration by use of a c..
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Funding Acknowledgements
We acknowledge grant support from the National Health and Medical Research Council, Canberra, ACT, Australia, the Samuel Nissen Charitable Foundation managed by Perpetual, Melbourne, VIC, Australia, the Murdoch Children's Research Institute, Melbourne, VIC, Australia, and the Victorian Government's Operational Infrastructure Support Program. We thank the participating families, the PREDICT research assistants, and all the study clinicians, without whose help this study could not have been undertaken.