The relationship between retinal vessel calibre and knee cartilage and BMLs
Miranda L Davies-Tuck, Ryo Kawasaki, Anita Wluka, Tien Y Wong, Lauren Hodgson, Dallas R English, Graham G Giles, Flavia M Cicuttini
BMC MUSCULOSKELETAL DISORDERS | BMC | Published : 2012
BACKGROUND: Whether the increase in vascular disease prevalence and mortality in OA populations is a result of co-occurrence of cardiovascular disease and OA, which are both common in the older population, is due to OA treatments or to the common association with reduced physical activity and/or obesity is unclear. One way to explore this non-invasively is to examine the cross-sectional relationship between changes in retinal microvasculature, which have been shown to be markers of generalized vascular pathology, and knee structural changes in an asymptomatic community-based population. METHODS: A community sample of 289 (61% women) aged 50-79 years with no knee symptoms underwent magnetic r..View full abstract
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Awarded by National Health and Medical Research Council (NHMRC)
The Melbourne Collaborative Cohort Study recruitment was funded by VicHealth and The Cancer Council of Victoria. This study was funded by a program grant from the National Health and Medical Research Council (NHMRC; 209057) and was further supported by infrastructure provided by The Cancer Council of Victoria. We would like to acknowledge the NHMRC (project grant 334150) and Colonial Foundation. Drs Wluka and Wang are the recipients of NHMRC Public Health Fellowships (317840 and 465142, respectively). Ms Davies-Tuck is the recipient of a Monash Bridging Fellowship. We would especially like to thank the study participants who made this study possible.