Journal article

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

Hina Kalra, Richard J Simpson, Hong Ji, Elena Aikawa, Peter Altevogt, Philip Askenase, Vincent C Bond, Francesc E Borras, Xandra Breakefield, Vivian Budnik, Edit Buzas, Giovanni Camussi, Aled Clayton, Emanuele Cocucci, Juan M Falcon-Perez, Susanne Gabrielsson, Yong Song Gho, Dwijendra Gupta, HC Harsha, An Hendrix Show all

PLOS BIOLOGY | PUBLIC LIBRARY SCIENCE | Published : 2012

Abstract

Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific..

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University of Melbourne Researchers

Grants

Awarded by NHMRC fellowship


Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE


Awarded by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES


Awarded by National Institute on Minority Health and Health Disparities


Funding Acknowledgements

This work was supported by a NH&MRC fellowship (1016599) and LIMS fellowship to SM. Part of tool development for data upload into Vesiclepedia was funded by the eResearch Office at La Trobe University with programming support from the Victorian eResearch Strategic Initiative (VeRSI). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.