Associations Between Helicobacter pylori Infection, Co-Morbid Infections, Gastrointestinal Symptoms, and Circulating Cytokines in African Children
Sarah Cherian, David Paul Burgner, Angus George Cook, Frank Mario Sanfilippo, David Alan Forbes
HELICOBACTER | WILEY | Published : 2010
BACKGROUND: Refugee children have complex medical needs and often have multiple infections. The relationship between infection, gastrointestinal symptoms, and systemic inflammation is poorly understood. We investigated these parameters in refugee children with a high prevalence of Helicobacter pylori, helminth, and malaria infection. MATERIALS AND METHODS: African refugee children were recruited at resettlement health screening. Data were collected on demography, gastrointestinal symptoms, co-morbid infection, and serum for peripheral cytokine levels. Helicobacter pylori infection was diagnosed by a fecal-based immunoassay. RESULTS: Data from 163 children were analyzed, of which 84.0% were p..View full abstract
This study was in part funded by a (1) 2007 University of Western Australia Research Grant and (2) 2007 Royal Australasian College of Physicians Grant (R + E Albert Award) awarded to SC for study consumables.