Journal article
Long-term outcomes of the australasian randomized clinical trial comparing laparoscopic and conventional open surgical treatments for colon cancer: the Australasian Laparoscopic Colon Cancer Study trial.
Philip F Bagshaw, Randall A Allardyce, Christopher M Frampton, Francis A Frizelle, Peter J Hewett, Paul J McMurrick, Nicholas A Rieger, J Shona Smith, Michael J Solomon, Andrew RL Stevenson, undefined Australasian Laparoscopic Colon Cancer Study Group
Ann Surg | Published : 2012
Abstract
OBJECTIVE: : We report a multicentered randomized controlled trial across Australia and New Zealand comparing laparoscopic-assisted colon resection (LCR) with open colon resection (OCR) for colon cancer. BACKGROUND: : Colon cancer is a significant worldwide health issue. This trial investigated whether the short-term benefits associated with LCR for colon cancer could be achieved safely, without survival disadvantages, in our region. METHODS: : A total of 601 patients with potentially curable colon cancer were randomized to receive LCR or OCR. Primary endpoints were 5-year overall survival, recurrence-free survival, and freedom from recurrence rates, compared using an intention-to-treat anal..
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