Journal article
Clinicopathologic features of incident and subsequent tumors in patients with multiple primary cutaneous melanomas
R Murali, C Goumas, A Kricker, L From, KJ Busam, CB Begg, T Dwyer, SB Gruber, PA Kanetsky, I Orlow, S Rosso, NE Thomas, M Berwick, RA Scolyer, BK Armstrong
Annals of Surgical Oncology | SPRINGER | Published : 2012
Abstract
Background. 0.6-12.7% of patients with primary cutaneous melanoma will develop additional melanomas. Pathologic features of tumors in patients with multiple primary cutaneous melanomas have not been well described. In this large, international, multicenter, case-control study, we compared the clinicopathologic features of a subsequent melanoma with the preceding (usually the first) melanoma in patientswith multiple primary cutaneous melanomas, and with those of melanomas in patients with single primary cutaneous melanomas. Methods. Multiple primary melanoma (cases) and single primary invasive melanoma (controls) patients from the Genes, Environment and Melanoma (GEM) study were included if t..
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Awarded by National Institutes of Health
Funding Acknowledgements
This work is supported by the following NIH/NCI grants: U01 CA83180, R01 CA112425, R01 CA112243, and R01 CA112243-05S1. Professor Scolyer is a Cancer Institute New South Wales Clinical Research Fellow.