Journal article
Nosocomial vs community-acquired pandemic influenza A (H1N1) 2009: A nested case-control study
G Khandaker, H Rashid, Y Zurynski, PC Richmond, J Buttery, H Marshall, M Gold, T Walls, B Whitehead, EJ Elliott, R Booy
Journal of Hospital Infection | W B SAUNDERS CO LTD | Published : 2012
Abstract
Background: The characteristics of nosocomial influenza in children are not well described. Aim: To compare the characteristics of nosocomial and community-acquired pandemic influenza A (H1N1) 2009 (pH1N1) in Australian children. Methods: In a nested case-control study, the clinical and epidemiological features of nosocomial vs community-acquired pH1N1 were compared among hospitalized children aged <15 years in six paediatric hospitals in Australia between 1 June and 30 September 2009. Findings: Of 506 hospitalized children with pH1N1, 47 (9.3%) were of nosocomial origin. These 47 cases were compared with 141 gender- and age-matched controls. Cases had a significantly higher proportion of un..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
RB has received financial support from CSL, Sanofi, GlaxoSmithKline, Novartis, Roche and Wyeth to conduct research and attend and present at scientific meetings. Any funding received is directed to an NCIRS research account at The Children's Hospital at Westmead and is not personally accepted by RB. HM has participated as a board member of global advisory boards for Merck and GlaxoSmithKline, and has participated as an investigator in industry-sponsored clinical vaccine trials. JB has served on advisory and/or data safety monitoring committees for CSL Vaccines and GlaxoSmithKline, for which the Murdoch Children's Research Institute receives payments into an educational fund. The other authors declare that they have no conflict of interest in relation to this work.This project was funded, in part, by the New South Wales Department of Health and the National Health and Medical Research Council (NHMRC) H1N1 Grant No: 633028. Activities of the APSU and NCIRS are supported by the Australian Government Department of Health and Ageing. APSU is supported by the NHMRC (Enabling Grant No: 402784 and Practitioner Fellowship No: 457084, E. Elliott), NHMRC Career Development Fellowship (No. 1016272 H. Marshall), the Discipline of Paediatrics and Child Health and Faculty of Medicine, University of Sydney; the Children's Hospital at Westmead; and the Royal Australasian College of Physicians.