Journal article
Role of human papillomaviruses in esophageal squamous cell carcinoma
SS Liyanage, E Segelov, SM Garland, SN Tabrizi, H Seale, PJ Crowe, DE Dwyer, A Barbour, AT Newall, A Malik, CR Macintyre
Asia Pacific Journal of Clinical Oncology | WILEY | Published : 2013
Abstract
Esophageal cancer (EC) is responsible for almost half a million deaths worldwide annually and has a multifactorial etiology, which may account for its geographical variation in incidence. In the last 30 years the potential of human papillomaviruses (HPV) as oncogenes or co-factors in the tumorigenic process of esophageal squamous cell carcinoma (ESCC) has been widely studied. While the etiology of HPV in cervical and certain other anogenital and aerodigestive cancers has been established, results regarding its role in EC have been largely inconclusive. A causal association can be evaluated only with a case-control study, where normal controls are compared to ESCC cases for the presence of HP..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
[ "ATN currently holds a National Health and Medical Research Council Training Fellowship (630724 - Australian-based Public Health Fellowship).", "SG has received advisory board fees and grant support from Commonwealth Serum Laboratories and GlaxoSmithKline, and lecture fees from Merck, GlaxoSmithKline and Sanofi Pasteur; in addition, she has also received funding through her institution to conduct human papillomavirus vaccine studies for Merck Sharp Dohme and GlaxoSmithKline. She is a member of the Merck Global Advisory Board as well as the Merck Scientific Advisory Committee for HPV." ]