Conference Proceedings

Emotional reactivity following surgery to the prefrontal cortex

Lisanne M Jenkins, David G Andrewes, Christian L Nicholas, Katharine J Drummond, Bradford A Moffat, Pramit M Phal, Patricia Desmond

JOURNAL OF NEUROPSYCHOLOGY | WILEY | Published : 2018

Abstract

We aimed to elicit emotion in patients with surgically circumscribed lesions of the prefrontal cortex (PFC) in order to elucidate the precise functional roles in emotion processing of the discrete subregions comprising the ventromedial PFC, including the medial PFC and orbitofrontal cortex (OFC). Three components of emotional reactivity were measured: subjective experience, behaviour, and physiological response. These included measures of self-reported emotion, observer-rated facial expression of emotion and measurements of heart rate and heart rate variability (HRV) during film viewing, and a measure of subjective emotional change since surgery. Patients with lesions to the ventromedial PFC..

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