Journal article
Breast-feeding and childhood-onset type 1 diabetes: A pooled analysis of individual participant data from 43 observational studies
CR Cardwell, LC Stene, J Ludvigsson, J Rosenbauer, O Cinek, J Svensson, F Perez-Bravo, A Memon, SG Gimeno, EJK Wadsworth, ES Strotmeyer, MJ Goldacre, K Radon, LM Chuang, RC Parslow, A Chetwynd, K Karavanaki, G Brigis, P Pozzilli, B Urbonaite Show all
Diabetes Care | AMER DIABETES ASSOC | Published : 2012
DOI: 10.2337/dc12-0438
Abstract
OBJECTIVE - To investigate if there is a reduced risk of type 1 diabetes in children breastfed or exclusively breastfed by performing a pooled analysis with adjustment for recognized confounders. RESEARCH DESIGN AND METHODS - Relevant studies were identified from literature searches using MEDLINE, Web of Science, and EMBASE. Authors of relevant studies were asked to provide individual participant data or conduct prespecified analyses. Meta-analysis techniques were used to combine odds ratios (ORs) and investigate heterogeneity between studies. RESULTS - Data were available from 43 studies including 9,874 patients with type 1 diabetes. Overall, there was a reduction in the risk of diabetes af..
View full abstractGrants
Awarded by National Institute of Diabetes and Digestive and Kidney Diseases
Funding Acknowledgements
This work was supported by National Institutes of Health grants R01-DK-46498 and R01-DK-42316, the Chinese Foundation of Health, a grant (DOH91-TD1167) from the Department of Health, Executive Yuan, Republic of China, the Ministry for Science and Technology of the Republic of Serbia through Contract 175042 (2011-2014), a grant from the German Research Foundation (HE 234/1-1), and the Research Council of Norway (148359/330).