Journal article
Mesoporous gadolino-aluminosilicate nanoparticles as magnetic resonance imaging contrast agents
NMK Tse, DF Kennedy, N Kirby, BA Moffat, TM Hinton, BW Muir, RA Caruso, CJ Drummond
Journal of Materials Chemistry B | ROYAL SOC CHEMISTRY | Published : 2013
DOI: 10.1039/c3tb00034f
Abstract
Enhanced T1 MRI contrast was observed in mesoporous gadolinosilicates co-doped with aluminium. The effect of gadolinium and aluminium dopant concentration was explored using a high-throughput workflow. The T1 relaxivity increases with lower gadolinium and higher aluminium loadings. © 2013 The Royal Society of Chemistry.
Grants
Awarded by Australian Research Council Future Fellowship
Funding Acknowledgements
We thank Chris Sheedy (CSIRO Process Science and Engineering) for performing the ICP-OES analyses. TEM images were conducted at the Bio21 Institute of The University of Melbourne. Portions of this research were undertaken on the SAXS/WAXS beamline at the Australian Synchrotron, Victoria, Australia. N.M.K.T. was the recipient of a CSIRO PhD studentship, D.F.K. was the recipient of the CSIRO Office of the Chief Executive postdoctoral award, R.A.C acknowledges an Australian Research Council Future Fellowship (FT0990583), and C.J.D. was the recipient of an Australian Research Council Federation Fellowship.