Journal article
The Ludwig institute for cancer research Melbourne melanoma cell line panel
A Behren, M Anaka, PH Lo, LJ Vella, ID Davis, J Catimel, T Cardwell, C Gedye, C Hudson, R Stan, J Cebon
Pigment Cell and Melanoma Research | Published : 2013
DOI: 10.1111/pcmr.12097
Abstract
While a variety of mouse models of melanoma exist (Damsky and Bosenberg (2012) Pigment Cell Melanoma Res 25, 404-405), the resulting tumours may not display the same properties or targets as human melanoma cells. Experiments utilizing fresh human melanoma specimens are preferable, but are restricted by tissue availability. Therefore human cancer cell lines are still a valuable tool in melanoma research for the assessment of biological mechanisms behind cell behaviours, and for testing novel treatments in vitro or in vivo with xenografts. © 2013 John Wiley & Sons A/S.
Grants
Funding Acknowledgements
AB is supported by a fellowship from the Cure Cancer Australia Foundation. JC and AB are supported by a grant from the Melanoma Research Alliance (MRA) and JC is supported by a practitioner fellowship from the Nation Health and Medical Research Council (NHMRC). This research was supported in part by the Cancer Council Victoria (CCV), the Austin Medical Research Foundation (AHMRF) and Operational Infrastructure Support Program Funding of the Victorian State Government.