Journal article

Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion

Eric Hanssen, Chaitali Dekiwadia, David T Riglar, Melanie Rug, Leandro Lemgruber, Alan F Cowman, Marek Cyrklaff, Mikhail Kudryashev, Friedrich Frischknecht, Jake Baum, Stuart A Ralph

CELLULAR MICROBIOLOGY | WILEY | Published : 2013

Grants

Awarded by National Center for Research Resources


Awarded by National Institute of General Medical Sciences from the National Institutes of Health


Awarded by National Health and Medical Research Council of Australia (NHMRC)


Awarded by Australian Research Council


Awarded by Human Frontier Science Organisation (HFSP YI Program)


Awarded by US Department of Energy, Office of Biological and Environmental Research


Awarded by National Center for Research Resources of the National Institutes of Health


Awarded by Australian Research Council (ARC)


Funding Acknowledgements

The authors thank Carolyn Larabell, and Mark A. Le Gros (University of California, San Francisco) and Christian Knoechel (Lawrence Berkeley National Laboratory) for assistance and advice with X-ray tomography. X-ray tomography was conducted at the National Center for X-ray Tomography, supported by grants from the National Center for Research Resources (5P41RR019664-08) and the National Institute of General Medical Sciences (8 P41 GM103445-08) from the National Institutes of Health. Human erythrocytes were kindly provided by the Red Cross Blood Bank (Melbourne). This work was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC IRIISS. Funding for the research came from the National Health and Medical Research Council of Australia (NHMRC Project Grants 637340 and APP1047085 JB & SAR), The Australian Research Council (Discovery Project Grant DP120103161), and Human Frontier Science Organisation (HFSP YI Program Grant RGY0071/2011 J.B. and F. F.), the Australian Synchrotron and the Australian Academy of Science, the US Department of Energy, Office of Biological and Environmental Research (DE-AC02-05CH11231), the National Center for Research Resources of the National Institutes of Health (RR019664). Use of the Advanced Light Source was supported by the US Department of Energy, Office of Science. D. T. R. is supported by a Pratt Foundation PhD scholarship through the University of Melbourne; M. R. was supported by the Australian Academy of Science and a grant from the OzeMalaR Network. L. L. was supported by a Postdoctoral fellowship from the University of Heidelberg cluster of excellence CellNetworks. M. K. acknowledges support of the CINA grant from SystemX.ch and from Henning Stahlberg (University of Basel). J.B. and S. A. R. are supported by Australian Research Council (ARC) Future Fellowships (FT100100112 and FT0990350). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors have declared that no conflict of interest exists.