Journal article

Retinal amino acid neurochemistry in health and disease

Michael Kalloniatis, Chee Seang Loh, Monica L Acosta, Guido Tomisich, Yuan Zhu, Lisa Nivison-Smith, Erica L Fletcher, Jacqueline Chua, Daniel Sun, Niru Arunthavasothy

CLINICAL AND EXPERIMENTAL OPTOMETRY | TAYLOR & FRANCIS LTD | Published : 2013

Abstract

Advances in basic retinal anatomy, genetics, biochemical pathways and neurochemistry have not only provided a better understanding of retinal function but have also allowed us to link basic science to retinal disease. The link with disease allowed measures to be developed that now provide an opportunity to intervene and slow down or even restore sight in previously 'untreatable' retinal diseases. One of the critical advances has been the understanding of the retinal amino acid neurotransmitters, related amino acids, their metabolites and functional receptors. This review provides an overview of amino acid localisation in the retina and examples of how retinal anatomy and amino acid neurochem..

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University of Melbourne Researchers