Journal article

The use of fused PET/CT images for patient selection and radical radiotherapy target volume definition in patients with non-small cell lung cancer: Results of a prospective study with mature survival data

Michael P Mac Manus, Sarah Everitt, Mike Bayne, David Ball, Nikki Plumridge, David Binns, Alan Herschtal, Deborah Cruickshank, Mathias Bressel, Rodney J Hicks

RADIOTHERAPY AND ONCOLOGY | ELSEVIER IRELAND LTD | Published : 2013

Abstract

BACKGROUND AND PURPOSE: This prospective study investigated the impact of radiotherapy (RT)-planning FDG-PET/CT on management of non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Patients still eligible for radical RT after conventional staging underwent RT-planning PET/CT and, if disease was still treatable to 60 Gy, they entered our planning study, where visually-contoured tumour volumes derived with and without PET information were compared. If PET/CT detected advanced disease, palliative therapy was given. Overall survival (OS) for palliative and curative patients was compared. RESULTS: Of 76 eligible patients, only 50 (66%) received radical chemoRT after PET/CT while 26 (34%) r..

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