Journal article
Prevalence and concurrence of anxiety, depression and fatigue over time in multiple sclerosis
B Wood, IAF Van Der Mei, AL Ponsonby, F Pittas, S Quinn, T Dwyer, RM Lucas, BV Taylor
Multiple Sclerosis Journal | SAGE PUBLICATIONS LTD | Published : 2013
Abstract
Background: Anxiety, depression and fatigue are commonly reported by persons with multiple sclerosis (PwMS). Objectives: We estimated the prevalence of each factor in a representative sample of PwMS, and in subgroups defined by age, sex and disease duration, at cohort entry and over time. We further examined whether and how these factors clustered together. Methods: A population-based longitudinal cohort of 198 PwMS was followed 6-monthly for 2.5 years. The Hospital Anxiety and Depression Scale (HADS) was used to measure anxiety (cut-point >7) and depression (>7) and the Fatigue Severity Scale (FSS) to measure fatigue (≥5). Results: At cohort entry, prevalence of anxiety was 44.5% (95%CI 37...
View full abstractGrants
Awarded by National Health & Medical Research Council of Australia (NHMRC)
Awarded by Academy of Finland (AKA)
Funding Acknowledgements
This study was funded by the National Health & Medical Research Council of Australia (NHMRC grant number 211308).