Journal article

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Christopher Lupfer, Paul G Thomas, Paras K Anand, Peter Vogel, Sandra Milasta, Jennifer Martinez, Gonghua Huang, Maggie Green, Mondira Kundu, Hongbo Chi, Ramnik J Xavier, Douglas R Green, Mohamed Lamkanfi, Charles A Dinarello, Peter C Doherty, Thirumala-Devi Kanneganti

Nature Immunology | NATURE PUBLISHING GROUP | Published : 2013

University of Melbourne Researchers

Grants

Awarded by EU Framework Program 7


Awarded by European Research Council


Awarded by Fund for Scientific Research Flanders


Awarded by US National Institutes of Health


Awarded by NATIONAL CANCER INSTITUTE


Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE


Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES


Awarded by NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES


Awarded by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES


Funding Acknowledgements

We thank members of the Veterinary Pathology Core lab at St. Jude for their work in processing of hematoxylin and eosin-stained and immunohistochemistry slides, members of the Cell and Tissue Imaging Core facility for their help in preparing and imaging transmission electron microscopy samples, and A. Coyle, E. Grant, J. Bertin (Millennium Pharmaceuticals), T. Mak (University of Toronto) and R. Flavell (Yale University) for providing mutant mice. M. L. is supported by grants from the EU Framework Program 7 (Marie-Curie grant 256432), European Research Council (grant 281600) and the Fund for Scientific Research Flanders (G030212N, 1.2.201.10.N.00 and 1.5.122.11.N.00). This work was supported by US National Institutes of Health grants (AR056296, AI101935 and CA163507) and the American Lebanese Syrian Associated Charities to T.-D.K.