Association between Endothelial Dysfunction and Acute Brain Dysfunction during Critical Illness
Christopher G Hughes, Alessandro Morandi, Timothy D Girard, Bernhard Riedel, Jennifer L Thompson, Ayumi K Shintani, Brenda T Pun, E Wesley Ely, Pratik P Pandharipande
Anesthesiology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2013
Awarded by National Institutes of Health (Bethesda, Maryland)
Awarded by National Institutes of Health
Awarded by NATIONAL CENTER FOR RESEARCH RESOURCES
Awarded by NATIONAL INSTITUTE ON AGING
Received from the Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, Nashville, Tennessee. Submitted for publication March 27, 2012. Accepted for publication September 18, 2012. Dr. Hughes receives salary support from a Foundation for Anesthesia Education and Research (Rochester, Minnesota) Mentored Research Training Grant. Dr. Ely is supported by the VA Clinical Science Research and Development Service (Washington, District of Columbia) and the National Institutes of Health AG027472 (Bethesda, Maryland). Dr. Girard is supported by the National Institutes of Health AG034257 (Bethesda, Maryland). Drs. Ely and Girard are both supported by the Veterans Affairs Tennessee Valley Geriatric Research, Education and Clinical Center (Nashville, Tennessee). Dr. Riedel is supported by an International Anesthesia Research Society (San Francisco, California) Clinical Scholar Grant. This project was supported by a Vanderbilt Clinical and Translational Science Award grant UL1 RR024975 from the National Institutes of Health, Innovation Grant from Vanderbilt University Department of Anesthesiology (Nashville, Tennessee), and National Institutes of Health AG027472. Presented at the meeting of Society of Critical Care Medicine's 41st Critical Care Congress. February 6, 2012, Houston, Texas, and the American Society of Anesthesiologists Anesthesiology 2011 Annual Meeting, October 14, 2011, Chicago, Illinois. Figures 1 and 2 were redrawn by Annemarie B. Johnson, C.M.I., Medical Illustrator, Wake Forest University School of Medicine Creative Communications, Wake Forest University Medical Center, Winston-Salem, North Carolina.