Journal article

Magnetic spin imaging under ambient conditions with sub-cellular resolution

S Steinert, F Ziem, LT Hall, A Zappe, M Schweikert, N Goetz, A Aird, G Balasubramanian, L Hollenberg, J Wrachtrup

NATURE COMMUNICATIONS | NATURE RESEARCH | Published : 2013

Abstract

The detection of small numbers of magnetic spins is a significant challenge in the life, physical and chemical sciences, especially when room temperature operation is required. Here we show that a proximal nitrogen-vacancy spin ensemble serves as a high precision sensing and imaging array. Monitoring its longitudinal relaxation enables sensing of freely diffusing, unperturbed magnetic ions and molecules in a microfluidic device without applying external magnetic fields. Multiplexed charge-coupled device acquisition and an optimized detection scheme permits direct spin noise imaging of magnetically labelled cellular structures under ambient conditions. Within 20 s we achieve spatial resolutio..

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Grants

Awarded by Australian Research Council Centre of Excellence for Quantum Computation and Communication Technology


Funding Acknowledgements

This work was supported by Volkswagen Stiftung, Baden Wurttemberg Stiftung, DARPA via project QUASAR, the EU Projects Dinamo and SQUTEC, the German science foundation via the research group 1493 and the Australian Research Council Centre of Excellence for Quantum Computation and Communication Technology (CE110001027). We thank Chang Shin and Rainer Stohr for technical assistance with the resonator and the optical photolithography, respectively, and Friedemann Reinhard, Fedor Jelezko, Liam McGuiness and Phil Hemmer for helpful discussions.