Journal article
A wide-field suprachoroidal retinal prosthesis is stable and well tolerated following chronic implantation.
J Villalobos, DAX Nayagam, PJ Allen, P McKelvie, CD Luu, LN Ayton, AL Freemantle, M McPhedran, M Basa, CC McGowan, RK Shepherd, CE Williams
Investigative Ophthalmology Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2013
Abstract
The safety of chronic implantation of a retinal prosthesis in the suprachoroidal space has not been established. This study aimed to determine the safety of a wide-field suprachoroidal electrode array following chronic implantation using histopathologic techniques and electroretinography. A platinum electrode array in a wide silicone substrate was implanted unilaterally in the suprachoroidal space in adult cats (n = 7). The lead and connector were tunneled out of the orbit and positioned subcutaneously. Postsurgical recovery was assessed using fundus photography and electroretinography (ERG). Following 3 months of passive implantation, the animals were terminated and the eyes assessed for th..
View full abstractGrants
Awarded by National Health and Medical Research Council (NHMRC) Centre for Clinical Research Excellence Award
Funding Acknowledgements
Supported by the Ian Potter Foundation, John T. Reid Charitable Trusts, and the Australian Research Council, through its Special Research Initiative in Bionic Vision Science and Technology grant to Bionic Vision Australia (BVA). CERA receives Operational Infrastructure Support from the Victorian Government and is supported by a National Health and Medical Research Council (NHMRC) Centre for Clinical Research Excellence Award (#529923). The Bionics Institute (at St Vincent's Hospital) acknowledges the support it receives from the Victorian Government through its Operational Infrastructure Support Program.