Journal article
Cardiac MRI: A new gold standard for ventricular volume quantification during high-intensity exercise
A La Gerche, G Claessen, A Van De Bruaene, N Pattyn, J Van Cleemput, M Gewillig, J Bogaert, S Dymarkowski, P Claus, H Heidbuchel
Circulation Cardiovascular Imaging | Published : 2013
Abstract
Background-Accurate measures are critical when attempting to distinguish normal from pathological changes in cardiac function during exercise, yet imaging modalities have seldom been assessed against invasive exercise standards. We sought to validate a novel method of biventricular volume quantification by cardiac MRI (CMR) during maximal exercise. Methods and Results-CMR was performed on 34 subjects during exercise and free-breathing with the use of an ungated real-time (RT-ungated) CMR sequence. ECG and respiratory movements were retrospectively synchronized, enabling compensation for cardiac cycle and respiratory phase. Feasibility of RT-ungated imaging was compared with standard exercise..
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Funding Acknowledgements
This study was funded by a grant from the Fund for Scientific Research Flanders (FWO), Belgium. Dr La Gerche is funded by a postdoctoral scholarship from the National Health and Medical Research Council of Australia (NHMRC). The authors would like to thank Rotary International Tienen, Belgium for their contribution toward the CMR ergometer purchase.