Journal article
Factors affecting subjective memory complaints i. The AIBL aging study: Biomarkers, memory, affect, and age
R Buckley, MM Saling, D Ames, CC Rowe, NT Lautenschlager, SL MacAulay, RN Martins, CL Masters, T O'Meara, G Savage, C Szoeke, VL Villemagne, KA Ellis
International Psychogeriatrics | CAMBRIDGE UNIV PRESS | Published : 2013
Abstract
Background: The prognostic value of subjective memory complaints (SMCs) i. The diagnosis of dementia o. The Alzheimer's type is unclear. While some studies have found an association between SMCs and cognitive decline, many have found a stronger association with depression, which raises questions about their diagnostic utility. Methods: We examine. The cross-sectional association between SMC severity (as measured usin. The MAC-Q, a brief SMC questionnaire) and affect, memory, and Alzheimer's disease (AD) biomarkers (β-amyloid deposition an. The apolipoprotein E Î4 (APOEÎ4) allele) in healthy elderly controls (HC; M = 78.74 years, SD = 6.7) and individuals with mild cognitive impairment (MCI; ..
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Funding Acknowledgements
CSIRO and the Science and Industry Endowment Fund supported this research. The AIBL study also received support from NHMRC and Pfizer. We thank all the participants who took part in the study and the clinicians who referred MCI participants to the study.