Journal article

Predictors for developing intestinal failure in patients with Crohn's disease

Richard B Gearry, Michael A Kamm, Ailsa L Hart, Paul Bassett, Simon M Gabe, Jeremy M Nightingale

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | WILEY | Published : 2013

Abstract

BACKGROUND AND AIM: Intestinal failure (IF) is a rare but devastating complication of Crohn's disease (CD). The clinical and surgical factors that predispose to IF are poorly understood. The aim of this study was to define clinical factors that predispose to IF. METHODS: A retrospective case-control study was performed using consecutive CD patients with IF who were identified from a prospective database. Local population-based controls were selected with which to compare demographic, phenotypic, and clinical outcomes. RESULTS: Eighty-two CD patients requiring long-term intravenous fluids or nutrition were studied. Diagnosis at age 16 years or less (P = 0.01) and a family history of inflammat..

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