Cryogels for biomedical applications
Timothy MA Henderson, Katharina Ladewig, David N Haylock, Keith M McLean, Andrea J O'Connor
JOURNAL OF MATERIALS CHEMISTRY B | ROYAL SOC CHEMISTRY | Published : 2013
The use of hydrogels as support materials for the growth and proliferation of mammalian cells has been well documented as they closely mimic the gel-like properties - and in some cases also the chemical properties - of the extracellular matrix (ECM), which naturally surrounds the cells of any biological tissue. Macro-porous hydrogels set below the freezing point of the solvent, so-called 'cryogels', have recently gained significant interest in the fields of tissue engineering and in vitro cell culture, thanks to their inherent interconnected macro-porous structure and ease of formation in comparison to other macro-pore forming techniques. This review highlights recent advances in cryogelatio..View full abstract
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Awarded by Australian Research Council (ARC)
T.M.A. Henderson would like to thank The University of Melbourne, the Commonwealth Scienticic and Industrial Research Organisation (CSIRO), and the Melbourne Materials Institute (MMI) for various scholarships. K. Ladewig and D.N. Haylock would like to acknowledge financial support from the Australian Research Council (ARC) in the form of an ARC Super Science Fellowship (FS 110200025) and an ARC Future Fellowship (FT0991968), respectively.