Journal article

Residual Ischemia After Revascularization in Multivessel Coronary Artery Disease: Insights From Measurement of Absolute Myocardial Blood Flow Using Magnetic Resonance Imaging Compared With Angiographic Assessment

Jayanth R Arnold, Theodoros D Karamitsos, William J van Gaal, Luca Testa, Jane M Francis, Paul Bhamra-Ariza, Ali Ali, Joseph B Selvanayagam, Steve Westaby, Rana Sayeed, Michael Jerosch-Herold, Stefan Neubauer, Adrian P Banning



BACKGROUND: Revascularization strategies for multivessel coronary artery disease include percutaneous coronary intervention and coronary artery bypass grafting. In this study, we compared the completeness of revascularization as assessed by coronary angiography and by quantitative serial perfusion imaging using cardiovascular magnetic resonance. METHODS AND RESULTS: Patients with multivessel coronary disease were recruited into a randomized trial of treatment with either coronary artery bypass grafting or percutaneous coronary intervention. Angiographic disease burden was determined by the Bypass Angioplasty Revascularization Investigation (BARI) myocardial jeopardy index. Cardiovascular mag..

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University of Melbourne Researchers


Awarded by National Institute for Health Research

Funding Acknowledgements

This work was supported by the British Heart Foundation, the UK Medical Research Council, and the Oxford NIHR Biomedical Research Center. Contributions to the cost of the study were made by unrestricted research donation from both Cordis, a Johnson & Johnson Company, and Boston Scientific Corp.