Journal article
Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: Data linkage study of 11 million Australians
JD Mathews, AV Forsythe, Z Brady, MW Butler, SK Goergen, GB Byrnes, GG Giles, AB Wallace, PR Anderson, TA Guiver, P McGale, TM Cain, JG Dowty, AC Bickerstaffe, SC Darby
BMJ Online | Published : 2013
DOI: 10.1136/bmj.f2360
Open access
Abstract
Objective: To assess the cancer risk in children and adolescents following exposure to low dose ionising radiation from diagnostic computed tomography (CT) scans. Design: Population based, cohort, data linkage study in Australia. Cohort members: 10.9 million people identified from Australian Medicare records, aged 0-19 years on 1 January 1985 or born between 1 January 1985 and 31 December 2005; all exposures to CT scans funded by Medicare during 1985-2005 were identified for this cohort. Cancers diagnosed in cohort members up to 31 December 2007 were obtained through linkage to national cancer records. Main outcome: Cancer incidence rates in individuals exposed to a CT scan more than one yea..
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Awarded by Medical Research Council
Funding Acknowledgements
This research was funded by the Australian government via the National Health and Medical Research Council, and supported by in-kind contributions of people funded by the Cancer Research Campaign UK or employed by other agencies. The funding bodies had no role in study design, data analysis, or reporting; government agencies contributed to data collection and data linkage, but did not control data analysis, interpretation, or writing of the report. The corresponding author had full access to all data in the study, and had ultimate responsibility for data integrity, statistical analysis, and the decision to submit for publication.