Journal article
High genetic diversity of plasmodium vivax on the north coast of papua new guinea
A Arnott, C Barnadas, N Senn, P Siba, I Mueller, JC Reeder, AE Barry
American Journal of Tropical Medicine and Hygiene | Published : 2013
Abstract
Despite having the highest Plasmodium vivax burden in the world, molecular epidemiological data from Papua New Guinea (PNG) for this parasite remain limited. To investigate the molecular epidemiology of P. vivax in PNG, 574 isolates collected from four catchment sites in East Sepik (N = 1) and Madang (N = 3) Provinces were genotyped using the markers MS16 and msp1F3. Genetic diversity and prevalence of P. vivax was determined for all sites. Despite a P. vivax infection prevalence in the East Sepik (15%) catchments less than one-half the prevalence of the Madang catchments (27-35%), genetic diversity was similarly high in all populations (He = 0.77-0.98). High genetic diversity, despite a mar..
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Awarded by National Health and Medical Research Council (NHMRC) of Australia
Funding Acknowledgements
This work was supported by Project Grants 1003825 and 1010203 from the National Health and Medical Research Council (NHMRC) of Australia and the Bill and Melinda Gates Foundation. J.C.R. was supported by an NHMRC Principal Research Fellowship. This work was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC Independent Research Institutes Infrastructure Support Scheme (IRIISS).