Journal article

The C-terminal flanking peptide of progastrin induces gastric cell apoptosis and stimulates colonic cell division in vivo

Kathryn M Marshall, Oneel Patel, Gianni Bramante, Marie Laval, Mildred Yim, Graham S Baldwin, Arthur Shulkes

PEPTIDES | ELSEVIER SCIENCE INC | Published : 2013

DOI: 10.1016/j.peptides.2013.05.009

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Related Projects (2)

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GASTRINS AND COLORECTAL CANCER

My major goal for the past 20 years has been to understand how hormones such as gastrin stimulate the development of gastrointestinal cancer..

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Role of gastrin prohormones in the development of gastrointestinal cancers

Gastrin is a stomach hormone which increases acid secretion and the growth of the stomach and bowel. This growth promoting effect may be inv..

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Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This work was supported by grants 1006245 (AS, KMM, GSB) and 1020983 (GSB) from the National Health and Medical Research Council of Australia.

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Keywords

Rpmi
Male
Standard Error of the Mean
Protein Precursors
Ecl
Cell Proliferation
Neoplasm Transplantation
Neoplasm Invasiveness
Crc
Fetal Bovine Serum
Cell Division
Biochemistry & Molecular Biology
Peptide Fragments
Cell Movement
Heterografts
Progastrin
Model
Vector Only
Liver Neoplasms
Mice, Scid
Mouse
Pharmacology & Pharmacy
Gastric Mucosa
Science & Technology
Enterochromaffin-Like
Glycine-Extended Gastrin
Mice
Ctfp
Ci
Gastrin Knockout
Mice, Knockout
Curie
Gasko
Biological-Activity
Barretts Esophageal
Pg
Amidated Gastrin
Apoptosis
C-Terminal Flanking Peptide
Humans
4-(2-Hydroxyethyl)-1-Piperazineethanesulfonic Acid
Endocrinology & Metabolism
Gray
Glycine Extended Gastrin
Phosphate Buffered Saline
Dmem
Roswell Park Memorial Institute Medium
Female
Life Sciences & Biomedicine
Identification
As
Cancer
Dulbecco'S Modified Eagle'S Medium
Inhibits Apoptosis
Sem
Vo
Gy
Proliferation
Fbs
Cancer Cells
Pbs
Antisense
Secretion
Cell Line, Tumor
Animals
Gastrins
Mice, Inbred Cba
Gamide
Growth
Hepes
Ggly