Journal article

The C-terminal flanking peptide of progastrin induces gastric cell apoptosis and stimulates colonic cell division in vivo

Kathryn M Marshall, Oneel Patel, Gianni Bramante, Marie Laval, Mildred Yim, Graham S Baldwin, Arthur Shulkes

Peptides | ELSEVIER SCIENCE INC | Published : 2013

DOI: 10.1016/j.peptides.2013.05.009

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Related Projects (2)

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Gastrins And Colorectal Cancer

My major goal for the past 20 years has been to understand how hormones such as gastrin stimulate the development of gastrointestinal cancer..

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Role Of Gastrin Prohormones In The Development Of Gastrointestinal Cancers

Gastrin is a stomach hormone which increases acid secretion and the growth of the stomach and bowel. This growth promoting effect may be inv..

Grants

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This work was supported by grants 1006245 (AS, KMM, GSB) and 1020983 (GSB) from the National Health and Medical Research Council of Australia.

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Keywords

Liver Neoplasms
Gastric Mucosa
Mice, Knockout
Antisense
Cell Movement
Barretts Esophageal
Neoplasm Transplantation
Standard Error of the Mean
Life Sciences & Biomedicine
Inhibits Apoptosis
Gy
Mouse
Crc
Phosphate Buffered Saline
Neoplasm Invasiveness
Gasko
Gamide
Enterochromaffin-Like
Animals
Growth
Cell Division
Pharmacology & Pharmacy
Sem
Progastrin
Secretion
Male
Ecl
Glycine Extended Gastrin
Endocrinology & Metabolism
Heterografts
Humans
Cell Proliferation
Fetal Bovine Serum
Cancer Cells
Model
Apoptosis
Mice
Identification
Amidated Gastrin
Pbs
Biological-Activity
Mice, Scid
C-Terminal Flanking Peptide
Fbs
Cell Line, Tumor
Mice, Inbred Cba
Science & Technology
Biochemistry & Molecular Biology
Rpmi
Hepes
Peptide Fragments
Cancer
Vo
Glycine-Extended Gastrin
Pg
Gastrin Knockout
As
Ctfp
Dmem
Ci
Ggly
Dulbecco'S Modified Eagle'S Medium
Curie
Roswell Park Memorial Institute Medium
4-(2-Hydroxyethyl)-1-Piperazineethanesulfonic Acid
Vector Only
Female
Gastrins
Gray
Protein Precursors
Proliferation