A Possible Method to Predict Response to Non-Pharmacological Insomnia Therapy
Lisa M Campana, Gari D Clifford, John Trinder, Stephen D Pittman, Atul Malhotra
JOURNAL OF CLINICAL SLEEP MEDICINE | AMER ACAD SLEEP MEDICINE | Published : 2011
STUDY OBJECTIVES: To determine if electrocardiographic parameters are predictive of response to non-pharmacological insomnia therapy. DESIGN: Secondary analysis of heart rate parameters from a double blind, randomized, sham-controlled trial at multiple study sites. SETTING: Six sites in the United States were used for the data collection. PARTICIPANTS: One hundred ninety-eight healthy subjects with no sleep disorders. INTERVENTIONS: Subjects were studied on 2 consecutive nights, a baseline night and a therapy night. On the therapy night, subjects were phase advanced 4 h and randomized to receive either sham or vestibular stimulation, an experimental therapy for insomnia. MEASUREMENTS AND RES..View full abstract
Awarded by NIH
Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Dr. Malhotra has consulting and/or research income from Philips, Ethicon, Medtronic, SHC, SGS, Pfizer, Novartis, Sepracor, Cephalon, Apnex, Itamar, Merck, Apnicure. He is funded by NIH P01 HL095491, R01 HL085188, R01 HL090897, K24 HL 093218 and AHA. Dr. Clifford has received consulting and/or research income from Philips. Dr. Pittman is employed by Philips.