Journal article

Arterial carbon dioxide tension and outcome in patients admitted to the intensive care unit after cardiac arrest

Antoine G Schneider, Glenn M Eastwood, Rinaldo Bellomo, Michael Bailey, Miklos Lipcsey, David Pilcher, Paul Young, Peter Stow, John Santamaria, Edward Stachowski, Satoshi Suzuki, Nicholas C Woinarski, Janine Pilcher



BACKGROUND: Arterial carbon dioxide tension (PaCO2) affects neuronal function and cerebral blood flow. However, its association with outcome in patients admitted to intensive care unit (ICU) after cardiac arrest (CA) has not been evaluated. METHODS AND RESULTS: Observational cohort study using data from the Australian New Zealand (ANZ) Intensive Care Society Adult-Patient-Database (ANZICS-APD). Outcomes analyses were adjusted for illness severity, co-morbidities, hypothermia, treatment limitations, age, year of admission, glucose, source of admission, PaO2 and propensity score. We studied 16,542 consecutive patients admitted to 125 ANZ ICUs after CA between 2000 and 2011. Using the APD-PaCO2..

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