Journal article

Limited role for surveillance PET-CT scanning in patients with diffuse large B-cell lymphoma in complete metabolic remission following primary therapy

CY Cheah, MS Hofman, M Dickinson, A Wirth, D Westerman, SJ Harrison, K Burbury, M Wolf, H Januszewicz, K Herbert, HM Prince, DA Carney, DS Ritchie, RJ Hicks, JF Seymour

British Journal of Cancer | Published : 2013

Abstract

Background:The usefulness of positron emission tomography with computed tomography (PET-CT) in the surveillance of patients with diffuse large B-cell lymphoma (DLBCL) in complete metabolic remission after primary therapy is not well studied.Methods:We performed a retrospective review of our database between 2002 and 2009 for patients with de novo DLBCL who underwent surveillance PET-CT after achieving complete metabolic response (CMR) following primary therapy.Results:Four-hundred and fifty scans were performed in 116 patients, with a median follow-up of 53 (range 8-133) months from completion of therapy. Thirteen patients (11%) relapsed: seven were suspected clinically and six were subclini..

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