Journal article
Pilot field trial of the EG95 vaccine against ovine cystic echinococcosis in Rio Negro, Argentina: Early impact and preliminary data
E Larrieu, E Herrero, G Mujica, JL Labanchi, D Araya, C Grizmado, A Calabro, G Talmon, G Ruesta, A Perez, A Gatti, G Santillán, M Cabrera, M Arezzo, M Seleiman, L Cavagión, MG Cachau, CA Alvarez Rojas, L Gino, CG Gauci Show all
Acta Tropica | Published : 2013
Abstract
Cystic echinococcosis is endemic in the Rio Negro province of Argentina. After 30 years of control using praziquantel in dogs the transmission rate to humans and sheep has decreased significantly, however transmission persists. The objective of the study is to assess the impact of the inclusion of the EG95 vaccine for sheep in the control programme, including analysis of the vaccine's operative feasibility in field conditions. The vaccine was applied in an area comprising four communities of native people including 79 farms with 3146 lambs and 311 dogs in total. Seventy one farms were designated as control areas where no vaccinations were undertaken while vaccinations of lambs undertaken on ..
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Funding Acknowledgements
Invaluable support for this work was provided by health workers Casimiro Prafil, Bernardo Geraghty, Miguel Lopez, Sixto Uribe, Lorena Marilef, Eugenio Calfual and Gustavo Tartaglia. We thank them and their communities of Anecon Grande, Nahuel Pan, Mamuel Choique, Lipeteren and Rio Chico. We thank to Lic. Mario Lamfri, CONAE, Argentina for your help in the spatial analysis. Funding is acknowledged from the Australian National Health and Medical Research Council grants 628320, 100354 and from National University of La Pampa, Argentine.