A conserved human T cell population targets mycobacterial antigens presented by CD1b

Ildiko Van Rhijn; Anne Kasmar; Annemieke de Jong; Stephanie Gras; Mugdha Bhati; Marieke E Doorenspleet; Niek de Vries; Dale I Godfrey; John D Altman; Wilco de Jager; Jamie Rossjohn; D Branch Moody

Journal article

A conserved human T cell population targets mycobacterial antigens presented by CD1b

Ildiko Van Rhijn, Anne Kasmar, Annemieke de Jong, Stephanie Gras, Mugdha Bhati, Marieke E Doorenspleet, Niek de Vries, Dale I Godfrey, John D Altman, Wilco de Jager, Jamie Rossjohn, D Branch Moody

Nature Immunology | NATURE PUBLISHING GROUP | Published : 2013

DOI: 10.1038/ni.2630

University of Melbourne Researchers

Dale Godfrey Author Microbiology and Immunology

Related Projects (3)

RESEARCH FELLOWSHIP

Professor Godfrey is an immunologist with a long standing history as a pioneer in the study of a specialised type of white blood cell, known..

IMMUNE REGULATION EFFECTOR FUNCTION AND THERAPY

We seek to understand how white blood cells detect and destroy disease, and how molecules of the immune system punch holes in diseased cells..

IMMUNE REGULATION EFFECTOR FUNCTION AND THERAPY

We seek to understand how white blood cells detect and destroy disease, and how molecules of the immune system punch holes in diseased cells..

Grants

Awarded by US National Institute of Allergy and Infectious Diseases

Awarded by Nederlands Wetenschappelijk Onderzoek (Meervoud)

Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Awarded by NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES

Funding Acknowledgements

We thank the Tetramer Core Facility of the US National Institutes of Health for CD1b protein; M. Turner, C. Seshadri and the Shattuck Hospital for clinical collaboration; L. Tan for technical help; and the beamline staff at the Australian synchrotron for assistance with data collection. Supported by the US National Institute of Allergy and Infectious Diseases (AI04393, AR048632 to D. B. M., and K08 AI089858 to A. K.) the Burroughs Wellcome Fund, Nederlands Wetenschappelijk Onderzoek (Meervoud 836.08.001 to I. V. R.), the National Health and Medical Research Council (D. I. G. and J.R.) and the Australian Research Council (S.G.).