Journal article
Folate intake and risk of pancreatic cancer: Pooled analysis of prospective cohort studies
Y Bao, DS Michaud, D Spiegelman, D Albanes, KE Anderson, L Bernstein, PA Van Den Brandt, DR English, JL Freudenheim, CS Fuchs, GG Giles, E Giovannucci, RA Goldbohm, N Håkansson, PL Horn-Ross, EJ Jacobs, CM Kitahara, JR Marshall, AB Miller, K Robien Show all
Journal of the National Cancer Institute | OXFORD UNIV PRESS INC | Published : 2010
DOI: 10.1093/jnci/djr431
Abstract
Background Epidemiological studies evaluating the association between folate intake and risk of pancreatic cancer have produced inconsistent results. The statistical power to examine this association has been limited in previous studies partly because of small sample size and limited range of folate intake in some studies. Methods We analyzed primary data from 14 prospective cohort studies that included 319 716 men and 542 948 women to assess the association between folate intake and risk of pancreatic cancer. Folate intake was assessed through a validated food-frequency questionnaire at baseline in each study. Study-specific relative risks (RRs) and 95% confidence intervals (CIs) were estim..
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Awarded by National Institutes of Health
Funding Acknowledgements
This study was supported by grants from the National Cancer Institute, National Institutes of Health, Bethesda, MD (CA55075 to W. C. Willett and CA124908 to C.S.F.).