Journal article

Mechanisms of disease: Cell death

RS Hotchkiss, A Strasser, JE McDunn, PE Swanson

New England Journal of Medicine | MASSACHUSETTS MEDICAL SOC | Published : 2009

Abstract

This review is a primer on the three main mechanisms of cell death: apoptosis, autophagy-associated cell death, and necrosis. The authors discuss the clinical implications of each of these types of cell death and indicate where advances in our understanding have inspired new forms of therapy. Copyright © 2009 Massachusetts Medical Society.

University of Melbourne Researchers

Grants

Awarded by National Institute of General Medical Sciences


Funding Acknowledgements

Supported by grants (GM44118 and GM55194) from the National Institutes of Health and by the Leukemia and Lymphoma Society of America, the National Health and Medical Research Council of Australia, and the Alan A. and Edith L. Wolff Foundation.